GAZA - The Israeli military said it struck Gaza overnight on Thursday, hours after it intercepted a rocket launched from Gaza and following appeals from the United States for all sides to calm escalating violence in Israel and the occupied West Bank.
There were no immediate reports of serious casualties.
The military said it had targeted rocket and weapon production sites used by Hamas, the Islamist group that runs the blockaded strip, in response to Wednesday's rocket launch.
As warning sirens sounded again in Israeli areas around the strip of warnings of more incoming rocket fire before dawn on Thursday, powerful explosions shook buildings and lit up the night sky over Gaza.
ALSO READ: Israel hits Gaza as the conflict flares after West Bank clashes.
There was no claim of responsibility for Wednesday's rocket from Hamas or the smaller Iran-backed Islamic Jihad movement, which fired rockets at Israel last week.
The Leftist Democratic Front for the Liberation of Palestine has launched rocket salvos at Israel on Thursday in response to the airstrikes and the systematic aggression against Palestinian prisoners in Israeli prisons, according to the armed wing of the leftist Democratic Front for the Liberation of Palestine.
A Palestinian gunman shot dead seven people near a synagogue in East Jerusalem and an Israeli attack on a West Bank refugee camp, killing 10 Palestinians, as a result of the exchange of fire.
The US Secretary of State Antony Blinken urged calm upon wrapping up a visit to the region on Tuesday, in which he reaffirmed Washington's support for a two-state solution to the decades-long conflict.
ALSO READ: Blinken's visit makes little progress'' on Israel-Palestinian peace.
The top US diplomat for the Middle East, Barbara Leaf, and the US special representative for Palestinian affairs, Hady Amr, remained behind to continue deescalation talks between the sides.
In a tweet after Wednesday's rocket launch, Israel's far-right National Security Minister Itamar Ben-Gvir, who oversees prisons, said he would push ahead with plans to toughen conditions for Palestinian prisoners.
READ MORE: Seven killed in synagogue attack as West Bank violence spirals.
He said that he had asked the security cabinet to convene and that the rocket fire from Gaza will not stop me from continuing to attempt to cancel summer camp conditions for murderous terrorists.
Israel has carried out near-daily raids in the West Bank since a spate of deadly attacks by Palestinians in Israel last year, leading to a bloody January in which 35 Palestinians were killed.