The closure of the shop is more about the people than the bricks and mortar business it was opened by Mrs Hankin and her mother, Irene, in 1972 at its original location in Court Arcade, but now it has gone on the market after three decades.
It is thought to have been the first shop to bring hippy goods to the area, something others in Darlington were not doing.
The original venue was put at risk of demolition when it moved to its present home in 1990.
Mrs Hankin said there had been a lot of memories inside the building, which has been put on the market by the landlord for about 125,000.
She said that we may close a few weeks earlier because there will be a lot of clearing out to do.
We will have to get rid of fixtures and fittings - I will miss it because it is a beautiful shop.
There are hundreds of photographs on the wall and I hope the business that takes it over will keep them, but it's up to them. Last year, the Guru Boutique co-founder said she needed time to grieve after the death of 80-year-old husband Ray and a recent cancer scare.
She said she did not feel responsible for renewing a lease on the building, which will expire at the end of June.
She said that online is okay, but it's not as personal as seeing people and our friends pop round and we can have a chin wag.