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Cryptocurrency markets are currently experiencing a period of sideways trading, with investors anticipating the potential impact of upcoming tariff announcements on Wednesday. Despite some bearish sentiment in the medium term, experts like BlackRock CEO Larry Fink and Tom Lee remain optimistic about Bitcoin's future, citing its potential to rival the US dollar as a global reserve currency and its strong technical outlook.

President Donald Trump has appointed journalist Sara Carter as the next director of the Office of National Drug Control Policy, praising her commitment to fighting the opioid and fentanyl crisis. Carter, a former Fox News contributor, supports medical marijuana and has no issue with legalizing cannabis for recreational use, as long as it is properly monitored.

The article explores a shift in pain management away from opioids toward new, non-addictive treatments developed by companies like Vertex Pharmaceuticals and Tonix Pharmaceuticals. It highlights Vertex’s recent FDA approval for an acute pain treatment and discusses the promising potential of Tonix’s candidate drug for fibromyalgia, along with the broader outlook for both acute and chronic pain markets.

Cryptocurrency markets are currently in a holding pattern, with prices trading sideways as investors await the impact of upcoming tariff announcements. Despite the cautious sentiment, positive developments such as BlackRock CEO Larry Fink's belief in Bitcoin's potential as a global reserve currency and MicroStrategy's significant Bitcoin purchase suggest a potential for future growth.

The S&P 500 has significantly underperformed global markets in the first quarter of 2023, marking a notable shift from recent years where U.S. stocks dominated. This underperformance is attributed to declining technology stocks and a strong energy sector, leading to revised earnings growth estimates and a surge in gold prices.