Genetically Modified Piglets Offer Hope for Organ Transplantation in Japan

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Genetically Modified Piglets Offer Hope for Organ Transplantation in Japan

## Genetically Modified Pigs Born in Japan for Potential Organ Transplants to Humans

Japanese researchers have successfully produced three piglets cloned from a genetically modified pig. This breakthrough could pave the way for xenotransplantation, the transplantation of animal organs into humans.

The piglets were born through a collaboration between Meiji University International Institute for Bio-Resource Research and PorMedTec, a Kawasaki-based company. The original genetically modified pig was created by eGenesis, a U.S. biotechnology company.

The goal of this research is to address the global shortage of human organs for transplantation. In Japan, only 3% of organ-failure patients receive organs from brain-dead donors. Xenotransplantation offers a potential solution to this critical issue.

The genetically modified pigs have undergone modifications to prevent rejection of their organs in humans. Researchers plan to transplant the pigs' kidneys into monkeys to verify the safety and efficacy of the organs. If successful, they hope to begin human trials by 2025.

This research holds significant promise for the future of medicine. By overcoming the challenges of organ rejection, xenotransplantation could save countless lives and improve the quality of life for patients with organ failure.